In Resident Evil 5, you cannot manually save your game. Instead, the game uses auto-saves at checkpoints. When you quit a session or finish a chapter, the game asks:

: This reverts your inventory to the state it was in at your last major save point (usually the start of the chapter), though you keep your stage completion records. The Patch History: What Changed?

On newer platforms like PS4, Xbox One, and Nintendo Switch, Capcom attempted to patch the "rotten egg" and item duplication glitches. These glitches relied on one player giving items to another and then quitting without saving (selecting "No" to the overwrite prompt).

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