The story spans approximately three weeks of the characters' lives, culminating in a dramatic finale in Panama that resets the stage for the third season. Key Characters and New Faces

The group includes Michael Scofield (Wentworth Miller), Lincoln Burrows (Dominic Purcell), Fernando Sucre (Amaury Nolasco), and the unpredictable T-Bag (Robert Knepper).

To reflect the cross-country nature of the plot, production moved from Chicago to the Dallas-Fort Worth metropolitan area in Texas. The region's diverse landscape allowed it to stand in for various U.S. states and even Panama.