Students "do" the science rather than just reading it.

The final step usually involves identifying the 23rd pair to determine the biological sex of the individual. 3. Diagnosis and Notation

A karyotype is an individual’s complete set of chromosomes. In a laboratory setting, scientists stop cell division during metaphase to capture a clear "map" of the DNA. Humans typically have 46 chromosomes. Pairs: These are arranged into 23 pairs. Autosomes: Pairs 1 through 22 are non-sex chromosomes.

If you are looking to implement this in a classroom or for self-study, these resources are industry standards: