Run the software and click the PC icon in the top-left corner.
The Gold Edition includes both the base game and the Venice expansion. Standard trainers often break after game updates, but offer more flexibility. Popular tables for Anno 1404 provide several high-impact features: Anno 1404 Gold Edition Cheat Engine
Open Anno 1404 Gold Edition (specifically the Anno4.exe or Addon.exe for Venice). Run the software and click the PC icon